LRP6/FILAMENTOUS-ACTIN SIGNALING FACILITATES OSTEOGENIC COMMITMENT IN MECHANICALLY INDUCED PERIODONTAL LIGAMENT STEM CELLS

LRP6/filamentous-actin signaling facilitates osteogenic commitment in mechanically induced periodontal ligament stem cells

Abstract Background Mechanotransduction mechanisms whereby periodontal ligament stem cells (PDLSCs) translate mechanical stress into biochemical signals and thereby trigger osteogenic programs necessary for alveolar bone remodeling are being deciphered.Low-density lipoprotein receptor-related protein 6 (LRP6), a Wnt transmembrane receptor, has been

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The Global Regulator PhoU Positively Controls Growth and Butenyl-Spinosyn Biosynthesis in Saccharopolyspora pogona

Butenyl-spinosyn, a highly effective biological insecticide, is produced by Saccharopolyspora pogona.However, its application has been severely hampered by its low yield.Recent studies have shown that PhoU plays a pivotal role in regulating cell growth, secondary metabolite biosynthesis and intracellular phosphate levels.Nevertheless, the function

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The Global Regulator PhoU Positively Controls Growth and Butenyl-Spinosyn Biosynthesis in Saccharopolyspora pogona

Butenyl-spinosyn, a highly effective biological insecticide, is produced by Saccharopolyspora pogona.However, its application has been severely hampered by its low yield.Recent studies have shown that PhoU plays a pivotal role in regulating cell growth, secondary metabolite biosynthesis and intracellular phosphate levels.Nevertheless, the function

read more